Not So Contrarian : Drink Only Water to Wash Down Drugs and Viagra

New reasons to avoid grapefruit and other juices when taking certain drugs.

Over the past three years succeedingly more specific studies have come out that basically saying certain drugs should not be taken with grapefruit juice.

New research shows that it’s probably best to avoid washing down drugs with ANY type of fruit juice.

Avoid drinking grapefruit juice and other juices when taking certain drugs, including some that are prescribed for fighting life-threatening conditions such as heart disease, cancer, organ-transplant rejection, and infection, the research says.

Grapefruit juice provides many nutrients, such as vitamin C and lycopene. But chemicals in grapefruit interfere with the enzymes that break down (metabolize) certain drugs in your digestive system. This can result in excessively high levels of these drugs in your blood and an increased risk of serious side effects.

The exact chemicals in grapefruit juice that cause this interaction aren’t known. But these chemicals are present in the pulp and peel of grapefruit as well as in the juice. For this reason, any grapefruit product — including dietary supplements that contain grapefruit bioflavonoids — can interact with certain medications. If you avoid grapefruit, you may also want to avoid tangelos, a hybrid grapefruit, and Seville oranges, a type of bitter orange often used to make marmalade and compotes. They may have a similar effect.

If you take any of these drugs, you should completely avoid grapefruit products, tangelos and Seville oranges, unless otherwise directed by your doctor. Waiting to take these medications — even up to 24 hours — after you drink grapefruit juice will not prevent an interaction.

The following drugs are known to have potentially serious interactions with grapefruit products, tangelos and Seville oranges :

Drugs Affected by Grapefruit (source : mayoclinic.com)
(source : mayoclinic.com)

Talk to your doctor or pharmacist if you have concerns about the effect of grapefruit products on any of the medications you take. Do your own due diligence and search the Internet using “grapefruit juice” and “drugs” as keywords.

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